Antibodies and Antigens
Total PSA
Total PSA assays (ie, assays for determination of Free PSA and PSA-ACT) require the use of antibodies recognizing exposed epitopes (ie, epitopes that are not influenced by the complex forma¬tion between PSA and ACT). PSA10 or PSA36 MAb as catching antibodies in combination with PSA66 MAb as detecting antibody is recommended for the design of highly sensitive and specific assays, which are not dependent on the proportion of Free PSA and PSA-ACT, (ie, equimolar response assays).
Additional clones may be available on request.
| MAb | Isotype | Form | Prod. no. | Comments |
|---|---|---|---|---|
| PSA10 | IgG1 | Purified | 304-01 | Exposed epitope specific for PSA |
| PSA29 | IgG1 | Purified | 311-01 | Exposed epitope |
| PSA36 | IgG1 | Purified | 306-01 | Exposed epitope specific for PSA |
| PSA42 | IgG1 | Purified | 312-01 | Exposed epitope |
| PSA66 | IgG1 | Purified | 310-01 | Exposed epitope expressed in PSA and hk2 |