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Q & A

THE MESOMARK® ASSAY

The following are answers to some of the questions you may have about the MESOMARK® assay, and its role in the management of mesothelioma. Please contact us with any additional questions you may have.

What is the MESOMARK assay and how does it relate to mesothelioma?
Why is the MESOMARK test performed?
How is the MESOMARK test performed?
What do the results of the MESOMARK test mean?
Where can I obtain additional information about the MESOMARK assay?

 

What is the MESOMARK assay and how does it relate to mesothelioma?
The MESOMARK assay is a simple blood test, using an Enzyme-Linked Immunosorbent Assay (ELISA) format, for the quantitative measurement of Soluble Mesothelin-Related Peptides (SMRP) in human serum. SMRP is a biomarker produced by mesothelioma cells that can be elevated in the serum of patients suffering from mesothelioma.

Why is the MESOMARK test performed?
The MESOMARK test is performed to measure the level of SMRP present in the serum. The MESOMARK blood test will be used to help determine the presence of mesothelioma. The MESOMARK test can also help measure a mesothelioma patient's response to therapy and determine if additional testing is required.

How is the MESOMARK test performed?
A blood sample is taken from the patient and then sent to a laboratory for testing to determine the level of SMRP present in the blood. The laboratory determines the amount of SMRP present in the blood by using monoclonal antibodies known to specifically bind to SMRP. By measuring the amount of bound antibodies, the laboratory can calculate the amount of SMRP present in the patient's blood.

What do the results of the MESOMARK test mean?
Physicians use the MESOMARK test results to assist them in making decisions about the management of patients with mesothelioma. Increasing results may be indicative of progressive disease conditions; decreasing or constant results may be indicative of response to therapy, or stable disease.

Where can I obtain additional information about the MESOMARK assay?
Ask your physician or go to our Education & Support section to learn more about the MESOMARK assay and mesothelioma.